Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Unexplained chronic cough | Refractory chronic cough | Coughs
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01528Naltrexone hydrochloride--
BADD_D01533Naproxen--
BADD_D01535Naratriptan--
BADD_D01536Naratriptan hydrochloride--
BADD_D01537Natalizumab--
BADD_D01539Nateglinide--
BADD_D01541Nebivolol0.000837%
BADD_D01544Nedocromil--
BADD_D01546Nefazodone--
BADD_D01547Nefazodone hydrochloride--
BADD_D01549Nelarabine--
BADD_D01558Nexium--
BADD_D01559Niacin--
BADD_D01562Nicorandil--
BADD_D01563Nicotinate--
BADD_D01564Nicotine0.015295%
BADD_D01565Nicotine alkaloid--
BADD_D01566Nifedipine--
BADD_D01567Nilotinib0.009413%
BADD_D01568Nilutamide--
BADD_D01570Nisoldipine--
BADD_D01576Nitrofurantoin0.000204%
BADD_D01581Nivolumab--
BADD_D01582Nizatidine--
BADD_D01590Nuvaring--
BADD_D01592Obeticholic acid0.017305%
BADD_D01593Obiltoxaximab--
BADD_D01595Octreotide acetate--
BADD_D01596Ofatumumab--
BADD_D01598Ofloxacin0.000167%
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ADReCS-Target
ADR Term Drug Name Target