Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Seizure
ADR ID BADD_A03956
ADR Hierarchy
17      Nervous system disorders
17.12      Seizures (incl subtypes)
17.12.03      Seizures and seizure disorders NEC
17.12.03.001      Seizure
Description A disorder characterized by a sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. [CTCAE] Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or "seizure disorder." [MeSH]
MedDRA Code 10039906
MeSH ID D012640
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Afebrile convulsion | Afebrile seizure | Classic fit | Convulsion | Convulsion (excl neonatal) | Convulsion (NOS) | Convulsion disorder | Convulsions | Convulsions aggravated | Convulsions generalised | Convulsions generalized | Convulsions NOS | Convulsions NOS aggravated | Convulsive disorder | Convulsive movements | Convulsive seizure | Disorder convulsive | First episode fitting | Fit | Fit (non-epileptic) | Fits NOS | Fitting | Generalised convulsion | Seizure | Seizure cerebral | Seizures | Seizures cerebral | Tetany-like seizure | Breakthrough seizure | Non-epileptic seizure | Prolonged seizure | Dialeptic seizure | Nonepileptic Seizures | Nonepileptic Seizure | Seizure, Nonepileptic | Seizures, Nonepileptic | Non-Epileptic Seizures | Non Epileptic Seizures | Non-Epileptic Seizure | Seizure, Non-Epileptic | Seizures, Non-Epileptic | Generalized Absence Seizures | Absence Seizure, Generalized | Absence Seizures, Generalized | Generalized Absence Seizure | Seizure, Generalized Absence | Seizures, Generalized Absence | Tonic-Clonic Seizures | Tonic Clonic Seizures | Seizures, Tonic-Clonic | Seizure, Tonic-Clonic | Seizures, Tonic Clonic | Tonic-Clonic Seizure | Generalized Tonic-Clonic Seizures | Generalized Tonic Clonic Seizures | Generalized Tonic-Clonic Seizure | Seizure, Generalized Tonic-Clonic | Seizures, Generalized Tonic-Clonic | Tonic-Clonic Seizure, Generalized | Tonic-Clonic Seizures, Generalized | Clonic Seizures | Seizures, Clonic | Clonic Seizure | Seizure, Clonic | Tonic Seizures | Seizures, Tonic | Seizure, Tonic | Tonic Seizure | Atonic Seizures | Atonic Seizure | Seizure, Atonic | Seizures, Atonic | Atonic Absence Seizures | Absence Seizure, Atonic | Absence Seizures, Atonic | Atonic Absence Seizure | Seizure, Atonic Absence | Seizures, Atonic Absence | Myoclonic Seizures | Myoclonic Seizure | Seizure, Myoclonic | Seizures, Myoclonic | Epileptic Seizures | Epileptic Seizure | Seizure, Epileptic | Seizures, Epileptic | Seizures, Sensory | Seizure, Sensory | Sensory Seizure | Sensory Seizures | Absence Seizures | Absence Seizure | Seizure, Absence | Petit Mal Convulsion | Convulsion, Petit Mal | Convulsive Seizures | Seizures, Convulsive | Convulsive Seizure | Seizure, Convulsive | Seizures, Motor | Motor Seizure | Motor Seizures | Seizure, Motor | Jacksonian Seizure | Seizure, Jacksonian | Seizures, Auditory | Auditory Seizure | Auditory Seizures | Seizure, Auditory | Seizures, Focal | Focal Seizure | Focal Seizures | Seizure, Focal | Partial Seizures | Partial Seizure | Seizure, Partial | Seizures, Partial | Seizures, Generalized | Generalized Seizure | Generalized Seizures | Seizure, Generalized | Seizures, Gustatory | Gustatory Seizure | Gustatory Seizures | Seizure, Gustatory | Seizures, Olfactory | Olfactory Seizure | Olfactory Seizures | Seizure, Olfactory | Convulsion, Non-Epileptic | Convulsion, Non Epileptic | Convulsions, Non-Epileptic | Non-Epileptic Convulsion | Non-Epileptic Convulsions | Seizures, Somatosensory | Seizure, Somatosensory | Somatosensory Seizure | Somatosensory Seizures | Seizures, Vertiginous | Seizure, Vertiginous | Vertiginous Seizure | Vertiginous Seizures | Seizures, Vestibular | Seizure, Vestibular | Vestibular Seizure | Vestibular Seizures | Seizures, Visual | Seizure, Visual | Visual Seizure | Visual Seizures | Complex Partial Seizures | Complex Partial Seizure | Partial Seizure, Complex | Partial Seizures, Complex | Seizure, Complex Partial | Seizures, Complex Partial | Single Seizure | Seizure, Single | Seizures, Single | Single Seizures
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01525Naloxone0.001297%
BADD_D01526Naloxone hydrochloride--
BADD_D01527Naltrexone--
BADD_D01533Naproxen0.000048%
BADD_D01534Naproxen sodium--
BADD_D01535Naratriptan--
BADD_D01536Naratriptan hydrochloride--
BADD_D01541Nebivolol0.000115%
BADD_D01546Nefazodone--
BADD_D01547Nefazodone hydrochloride--
BADD_D01549Nelarabine0.000280%
BADD_D01550Nelfinavir mesylate--
BADD_D01553Neostigmine--
BADD_D01554Neostigmine methylsulfate--
BADD_D01564Nicotine0.003448%
BADD_D01566Nifedipine0.000336%
BADD_D01569Nimodipine0.000151%
BADD_D01572Nitisinone0.034499%
BADD_D01573Nitrazepam--
BADD_D01574Nitric oxide--
BADD_D01579Nitroglycerin0.000258%
BADD_D01580Nitrous oxide--
BADD_D01582Nizatidine--
BADD_D01585Norethindrone--
BADD_D01587Norfloxacin--
BADD_D01588Nortriptyline0.000237%
BADD_D01589Nortriptyline hydrochloride--
BADD_D01595Octreotide acetate--
BADD_D01598Ofloxacin0.000083%
BADD_D01599Olanzapine0.005683%
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ADReCS-Target
ADR Term Drug Name Target