| Drug Name |
Acetazolamide sodium |
| Drug ID |
BADD_D00026 |
| Description |
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) |
| Indications and Usage |
For adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
S01EC01 |
| DrugBank ID |
DB00819
|
| KEGG ID |
D01196
|
| MeSH ID |
D000086
|
| PubChem ID |
13290219
|
| TTD Drug ID |
D0E1SW
|
| NDC Product Code |
67457-853; 63552-116 |
| Synonyms |
Acetazolamide | Acetazolam | Acetazolamide Sodium, (Sterile) | Acetazolamide, Monosodium Salt | Ak-Zol | Ak Zol | AkZol | Apo-Acetazolamide | Apo Acetazolamide | ApoAcetazolamide | Diacarb | Diamox | Diuramide | Défiltran | Edemox | Glauconox | Glaupax | Huma-Zolamide | Huma Zolamide | HumaZolamide | Acetadiazol |
