Description
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Expression
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Biological Properties

Proteome  -  SMDBP000001  ( Q8TD57 )

Description

  • IDSMDBP000001
  • NameDynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (HsADHC3) (Ciliary dynein heavy chain 3) (Dnahc3-b)
  • OrganismHomo sapiens (Human)
  • Gene SymbolDNAH3
  • Gene SynonymsDnahc3b; Hsadhc3; DNAHC3-B; DKFZp434N074; DNAHC3B; DLP3; HEL-36; HSADHC3; HDHC8
  • ChromosomeGRCh38 chr16:20933111-21159537; hg19 chr16:20944433-21170762
  • Gene Sequence
    ATGGGAGCTACAGGGCGCCTCGAGCTCACACTGGCCGCCCCTCCCCATCCGGGCCCAGCCTTTCAGCGTTCAAAAGCCAGGGAGACCCAAGGAGAGGAGGAAGGGAGTGAAATGCAGATCGCCAAAAGTGACTCCATACATCACATGAGCCACTCCCAGGGGCAGCCAGAGCTGCCTCCTCTGCCTGCTT Show more... 
  • Protein Sequence
    MGATGRLELTLAAPPHPGPAFQRSKARETQGEEEGSEMQIAKSDSIHHMSHSQGQPELPPLPASANEEPSGLYQTVMSHSFYPPLMQRTSWTLAAPFKEQHHHRGPSDSIANNYSLMAQDLKLKDLLKVYQPATISVPRDRTGQGLPSSGNRSSSEPMRKKTKFSSRNKEDSTRIKLAFKTSIFSPMKKE  Show more... 
  • Protein Length4116
  • Mass470771.0

Expression

  • Abundance
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    Organism part

    		 Protocol Analysis method Abundance Raw Data Provider
    12.98698
    21.74874
    8.59254
    18.61709
    17.01875

Biological Properties

  • General FunctionForce generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). {ECO:0000250}.
  • GO – Biological Processcilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]
  • GO – Cellular Componentaxonemal dynein complex [GO:0005858]; dynein complex [GO:0030286]; microtubule [GO:0005874]
  • GO – Molecular FunctionATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; microtubule motor activity [GO:0003777]; minus-end-directed microtubule motor activity [GO:0008569]