Description
External Links
#
Expression
#
Biological Properties

Proteome  -  SMDBP000007  ( B1AK88 )

Description

  • IDSMDBP000007
  • NameF-actin-capping protein subunit beta
  • OrganismHomo sapiens (Human)
  • Gene SymbolCAPZB
  • Gene SynonymsCAPB; CAPPB; CAPZ
  • ChromosomeGRCh38 chr1:19338775-19485539; hg19 chr1:19665269-19812033
  • Gene Sequence
    ATGTTCACTCCTGGGCACCCGGGGAAGTGGAAGCGCCGGGCCCTGCTGCGGGGGGGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGAGTGATCAGCAGCTGGACTGTGCCTTGGACCTAATGAGGCGCCTGCCTCCCCAGCAAATCGAGAAAAACCTCAGCGACCTGATCGA Show more... 
  • Protein Sequence
    MHPSRRSLPFPLNCQLARVGTADYGSPSDQSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSS  Show more... 
  • Protein Length301
  • Mass33781.0

Expression

  • Abundance
    Export

    Organism part

    		 Protocol Analysis method Abundance Raw Data Provider
    24.00006
    23.48777

Biological Properties

  • General FunctionF-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. {ECO:0000256|RuleBase:RU365078}.
  • GO – Biological Processactin cytoskeleton organization [GO:0030036]; barbed-end actin filament capping [GO:0051016]
  • GO – Cellular ComponentF-actin capping protein complex [GO:0008290]; sarcomere [GO:0030017]
  • GO – Molecular Functionactin binding [GO:0003779]