Description
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Expression
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Biological Properties

Proteome  -  SMDBP000088  ( Q8TBY8 )

Description

  • IDSMDBP000088
  • NamePolyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein)
  • OrganismHomo sapiens (Human)
  • Gene SymbolPMFBP1
  • Gene SynonymsSTAP
  • ChromosomeGRCh38 chr16:72116697-72173908; hg19 chr16:72152996-72206349
  • Gene Sequence
    AATAGAAGTTCACCAGCTGAGGACTACGAGGATATTGAGGACAATGTGGAGCAGAGCCCCAGCTGACTCATAAAGGACATGTAGCATGAGTAAAAAATAAACCTTCACGGTCGTAAGCCACTGAGACTTGGGGGTTGTTTGTTACTACACCATCACCTAGCCTGTCCCCACCAGGTTTATAACAAAGCTC Show more... 
  • Protein Sequence
    MKDEAGERDREVSSLNSKLLSLQLDIKNLHDVCKRQRKTLQDNQLCMEEAMNSSHDKKQAQALAFEESEVEFGSSKQCHLRQLQQLKKKLLVLQQELEFHTEELQTSYYSLRQYQSILEKQTSDLVLLHHHCKLKEDEVILYEEEMGNHNENTGEKLHLAQEQLALAGDKIASLERSLNLYRDKYQSSLS  Show more... 
  • Protein Length1007
  • Mass117494.0

Expression

  • Abundance
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    Organism part

    		 Protocol Analysis method Abundance Raw Data Provider
    21.47591
    22.23291
    20.67692

Biological Properties

  • General FunctionRequired for normal spermatogenesis (PubMed:1770140, PubMed:30032984, PubMed:30298696). It functions as a scaffold protein that attaches the sperm head-tail connecting piece to the nuclear envelope, thus maintaining sperm head and tail integrity (PubMed:30032984). May also be involved in the general organization of cellular cytoskeleton (By similarity). {ECO:0000250|UniProtKB:Q9WVQ0, ECO:0000269|PubMed:1770140, ECO:0000269|PubMed:30032984, ECO:0000269|PubMed:30298696}.
  • GO – Biological Processspermatogenesis [GO:0007283]
  • GO – Cellular Componentcytoplasm [GO:0005737]; sperm connecting piece [GO:0097224]