Description
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Expression
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Biological Properties

Proteome  -  SMDBP000151  ( Q6NUT2 )

Description

  • IDSMDBP000151
  • NameProbable C-mannosyltransferase DPY19L2 (EC 2.4.1.-) (Dpy-19-like protein 2) (Protein dpy-19 homolog 2)
  • OrganismHomo sapiens (Human)
  • Gene SymbolDPY19L2
  • Gene SynonymsFLJ32949; SPATA34; SPGF9
  • ChromosomeGRCh38 chr12:63558913-63669201; hg19 chr12:63952693-64062273
  • Gene Sequence
    AGTCCGTTGAGGCTGCCAGGCGAGTCAGGTCTCTCTGGACCTCGCCTGACTCGGCTGGGCTGTGCCTGAAATTGACCCAGCTCCACCATACTCCTTGATTATGAGAAAACAAGGAGTAAGCTCAAAGCGGCTGCAATCTTCCGGCCGCAGCCAGTCTAAGGGGCGGCGCGGGGCCTCCCTCGCCCGGGAG Show more... 
  • Protein Sequence
    MRKQGVSSKRLQSSGRSQSKGRRGASLAREPEVEEEMEKSALGGGKLPRGSWRSSPGRIQSLKERKGLELEVVAKTFLLGPFQFVRNSLAQLREKVQELQARRFSSRTTLGIAVFVAILHWLHLVTLFENDRHFSHLSSLEREMTFRTEMGLYYSYFKTIIEAPSFLEGLWMIMNDRLTEYPLIINAIKR  Show more... 
  • Protein Length758
  • Mass87374.0

Expression

  • Abundance
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    Organism part

    		 Protocol Analysis method Abundance Raw Data Provider
    23.43800
    24.67939
    20.20434
    25.58500
    24.99095
    27.87712

Biological Properties

  • General FunctionProbable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins. {ECO:0000250|UniProtKB:P34413}.; Required during spermatogenesis for sperm head elongation and acrosome formation (PubMed:21397063, PubMed:21397064). Plays also a role in acrosome attachment to the nuclear envelope (By similarity). {ECO:0000250|UniProtKB:P0CW70, ECO:0000269|PubMed:21397063, ECO:0000269|PubMed:21397064}.
  • GO – Biological Processprotein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406]; spermatid development [GO:0007286]
  • GO – Cellular Componentintegral component of membrane [GO:0016021]; nuclear inner membrane [GO:0005637]; nucleus [GO:0005634]
  • GO – Molecular Functionmannosyltransferase activity [GO:0000030]