Description
External Links
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Expression
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Loci
Biological Properties

Proteome  -  SMDBP000417  ( O75969 )

Description

  • IDSMDBP000417
  • NameA-kinase anchor protein 3 (AKAP-3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Cancer/testis antigen 82) (CT82) (Fibrous sheath protein of 95 kDa) (FSP95) (Fibrousheathin I) (Fibrousheathin-1) (Protein kinase A-anchoring protein 3) (PRKA3) (Sperm oocyte-binding protein)
  • OrganismHomo sapiens (Human)
  • Gene SymbolAKAP3
  • Gene SynonymsAKAP 110; AKAP110; CT82; FSP95; HEL159; PRKA3; SOB1
  • ChromosomeGRCh38 chr12:4615508-4649051; hg19 chr12:4724674-4758217
  • Protein Sequence
    MSEKVDWLQSQNGVCKVDVYSPGDNQAQDWKMDTSTDPVRVLSWLRRDLEKSTAEFQDVRFKPGESFGGETSNSGDPHKGFSVDYYNTTTKGTPERLHFEMTHKEIPCQGPRAQLGNGSSVDEVSFYANRLTNLVIAMARKEINEKIDGSENKCVYQSLYMGNEPTPTKSLSKIASELVNETVSACSRNA  Show more... 
  • Protein Length853
  • Mass94751.0

Expression

  • Abundance
    Export

    Organism part

    		 Protocol Analysis method Abundance Raw Data Provider
    22.14918
    24.07341
    23.43290
    29.05062
    28.70489
    33.33475

Loci

  • Sperm LociPrincipal piece

Sperm Loci

Immunocytochemistry of washed motile ejaculated human spermatozoa incubated with antibodies against epididymal secretory proteins and testicular proteins (right panels, merged micrographs of fluorescence staining). Red staining (by PI) indicates the nuclei and green staining (by FITC) indicates the location of HEL-S-137P on spermatozoa. Each bar represents 5 um.

Biological Properties

  • General FunctionMay function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.
  • GO – Biological Processacrosome reaction [GO:0007340]; blastocyst hatching [GO:0001835]; protein localization [GO:0008104]; single fertilization [GO:0007338]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]
  • GO – Cellular Componentacrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; sperm fibrous sheath [GO:0035686]; sperm midpiece [GO:0097225]; sperm principal piece [GO:0097228]
  • GO – Molecular Functionprotein kinase A binding [GO:0051018]