Description
External Links
#
Expression
#
Biological Properties

Proteome  -  SMDBP000437  ( Q9UFH2 )

Description

  • IDSMDBP000437
  • NameDynein axonemal heavy chain 17 (Axonemal beta dynein heavy chain 17) (Axonemal dynein heavy chain-like protein 1) (Ciliary dynein heavy chain 17) (Ciliary dynein heavy chain-like protein 1) (Dynein axonemal light chain 2)
  • OrganismHomo sapiens (Human)
  • Gene SymbolDNAH17
  • Gene SynonymsFLJ40457; DNEL2; DNAHL1
  • ChromosomeGRCh38 chr17:78423697-78577436; hg19 chr17:76419778-76573478
  • Gene Sequence
    ATGTGGCAGTTGGAGCCCCTCGAGGGAAGGGAGCCATTTTCTTTCCTGGTTTGGGAAAGAGTTGCTCATCAGTTTGCGGGAGAAGCTGTTTGCCTTCAGCTGATACACAGTGTAAGGAAAGGCCAAGATGACAATGGCCCCGGACGTCAGACTAGAGTATCTGGAGGAAGTTGCCTCCATCGTCCTGAAG Show more... 
  • Protein Sequence
    MTMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAGMIIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSLDNLLL  Show more... 
  • Protein Length4462
  • Mass509313.0

Expression

  • Abundance
    Export

    Organism part

    		 Protocol Analysis method Abundance Raw Data Provider
    18.09658
    10.03743
    24.46639
    24.10269
    28.81902

Biological Properties

  • General FunctionForce generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (Probable). Plays a major role in sperm motility, implicated in sperm flagellar assembly and beating (PubMed:31178125). {ECO:0000269|PubMed:31178125, ECO:0000305|PubMed:31178125}.
  • GO – Biological Processcilium-dependent cell motility [GO:0060285]; cilium movement [GO:0003341]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158]
  • GO – Cellular Componentaxonemal dynein complex [GO:0005858]; axoneme [GO:0005930]; dynein complex [GO:0030286]; microtubule [GO:0005874]; motile cilium [GO:0031514]; outer dynein arm [GO:0036157]; sperm flagellum [GO:0036126]
  • GO – Molecular FunctionATP binding [GO:0005524]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; microtubule motor activity [GO:0003777]; minus-end-directed microtubule motor activity [GO:0008569]