Description
External Links
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Expression
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Loci
Biological Properties

Proteome  -  SMDBP000494  ( Q5T2S8 )

Description

  • IDSMDBP000494
  • NameOuter dynein arm-docking complex subunit 2 (Armadillo repeat-containing protein 4)
  • OrganismHomo sapiens (Human)
  • Gene SymbolODAD2
  • ChromosomeGRCh38 chr10:27775186-27999500; hg19 chr10:28101097-28288008
  • Gene Sequence
    AGCGCGGGCGCAGAGCGTCTCTGGCGCGGGCATACGGTGCAACGGGTCCGCGGGAATCTTGGATGCGCGGAGGTCCCGAGACCAGGTGCGTGTGCTAAGCTCAGGTCTGAGCACGGTGGATCCCATGGGTGTGGCTCTGAGGAAATTGACGCAGTGGACTGCTGCCGGACATGGAACTGGAATCCTCGAA Show more... 
  • Protein Sequence
    MGVALRKLTQWTAAGHGTGILEITPLNEAILKEIIVFVESFIYKHPQEAKFVFVEPLEWNTSLAPSAFESGYVVSETTVKSEEVDKNGQPLLFLSVPQIKIRSFGQLSRLLLIAKTGKLKEAQACVEANRDPIVKILGSDYNTMKENSIALNILGKITRDDDPESEIKMKIAMLLKQLDLHLLNHSLKHI  Show more... 
  • Protein Length1044
  • Mass115679.0

Expression

  • Abundance
    Export

    Organism part

    		 Protocol Analysis method Abundance Raw Data Provider
    15.80850
    20.16877
    16.08136
    22.24771
    21.34943
    29.67958

Loci

  • Sperm LociNeck

Sperm Loci

Immunocytochemistry of washed motile ejaculated human spermatozoa incubated with antibodies against epididymal secretory proteins and testicular proteins (right panels, merged micrographs of fluorescence staining). Red staining (by PI) indicates the nuclei and green staining (by FITC) indicates the location of HTL-T-74n on spermatozoa. Each bar represents 5 um.

Biological Properties

  • General FunctionComponent of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule (By similarity). May be involved in a late step of axonemal outer dynein arm assembly (PubMed:23849778). {ECO:0000250|UniProtKB:Q96M63, ECO:0000269|PubMed:23849778}.
  • GO – Biological Processcilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356]; ventricular system development [GO:0021591]
  • GO – Cellular Componentaxoneme [GO:0005930]; ciliary base [GO:0097546]