Description
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Expression
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Biological Properties

Proteome  -  SMDBP000592  ( P21266 )

Description

  • IDSMDBP000592
  • NameGlutathione S-transferase Mu 3 (EC 2.5.1.18) (GST class-mu 3) (GSTM3-3) (hGSTM3-3)
  • OrganismHomo sapiens (Human)
  • Gene SymbolGSTM3
  • Gene SynonymsGST5; GSTB; GSTM3-3; GTM3
  • ChromosomeGRCh38 chr1:109733932-109741038; hg19 chr1:110276554-110283660
  • Gene Sequence
    GGTTGGTTCTGAGAAGGCTTCAAGGAATAGGCAGACATTTCAGCAAGGCTGCTGAGGAAGGATAGGCTGTGGAAATTAGGATGCAGCACTCCTGCCCGGGTCCCGCCTCGGGGTCGCCAGGCCCTGAACCCCAACGCCGGCATTAGTCGCGCCTGCGCACGGCCCTGTGGAGCCGCGGAGGCAAGGGACG Show more... 
  • Protein Sequence
    MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMC  Show more... 
  • Protein Length225
  • Mass26560.0

Expression

  • Abundance
    Export

    Organism part

    		 Protocol Analysis method Abundance Raw Data Provider
    30.27693
    33.09677
    29.05165
    27.17961
    27.83463
    35.25287
    19.30000
    13.30000

Biological Properties

  • General FunctionConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers. {ECO:0000269|PubMed:10587441}.
  • GO – Biological Processcellular detoxification of nitrogen compound [GO:0070458]; establishment of blood-nerve barrier [GO:0008065]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; response to estrogen [GO:0043627]; xenobiotic catabolic process [GO:0042178]
  • GO – Cellular Componentcytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; nucleus [GO:0005634]; sperm fibrous sheath [GO:0035686]
  • GO – Molecular Functionenzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]