Description
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Expression
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Biological Properties

Proteome  -  SMDBP000727  ( Q96HR9 )

Description

  • IDSMDBP000727
  • NameReceptor expression-enhancing protein 6 (Polyposis locus protein 1-like 1)
  • OrganismHomo sapiens (Human)
  • Gene SymbolREEP6
  • Gene SynonymsFLJ25383; TB2L1; REEP6.2; REEP6.1; C19orf32; DP1L1; Yip2f; RP77
  • ChromosomeGRCh38 chr19:1491181-1497927; hg19 chr19:1491180-1497926
  • Gene Sequence
    AGGCTGCGGGAAAGCGGTGCGCGTGCAGCGGGGTGGGTGCCCTGGTCCGCGGGCGAGCTCGAGCAGCCAACCCCGGGCGCGTCGGGGCCATGGACGGCCTGAGGCAGCGCGTGGAGCACTTCCTGGAGCAAAGGAACCTGGTCACCGAAGTGCTGGGGGCGCTGGAGGCCAAGACCGGGGTGGAGAAGCG Show more... 
  • Protein Sequence
    MDGLRQRVEHFLEQRNLVTEVLGALEAKTGVEKRYLAAGAVTLLSLYLLFGYGASLLCNLIGFVYPAYASIKAIESPSKDDDTVWLTYWVVYALFGLAEFFSDLLLSWFPFYYVGKCAFLLFCMAPRPWNGALMLYQRVVRPLFLRHHGAVDRIMNDLSGRALDAAAGITRNVLQVLARSRAGITPVAVA  Show more... 
  • Protein Length211
  • Mass23418.0

Expression

  • Abundance
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    Organism part

    		 Protocol Analysis method Abundance Raw Data Provider
    29.82087
    30.97343
    26.01987
    21.96782
    22.62077
    2.30000
    1.30000

Biological Properties

  • General FunctionRequired for correct function and survival of retinal photoreceptors (PubMed:27889058). Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity). {ECO:0000250|UniProtKB:Q9JM62, ECO:0000269|PubMed:27889058}.
  • GO – Biological Processdetection of light stimulus involved in visual perception [GO:0050908]; endoplasmic reticulum organization [GO:0007029]; regulation of intracellular transport [GO:0032386]
  • GO – Cellular Componentclathrin-coated vesicle membrane [GO:0030665]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; nucleus [GO:0005634]; photoreceptor inner segment [GO:0001917]