Description
External Links
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Expression
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Biological Properties

Transcriptome  -  SMDBT000007  ( A4GNT )

Description

  • IDSMDBT000007
  • Gene SymbolA4GNT
  • Namealpha-1,4-N-acetylglucosaminyltransferase
  • OrganismHomo sapiens (Human)
  • Gene Synonymsalpha4GnT
  • ChromosomeGRCh38 chr3:138123713-138133310; hg19 chr3:137842555-137851232
  • Gene Sequence
    GTCATTTCTAAGACCTCAAATACTGGTTAACTGCATTTGCAGCTAGAAGTTAGGCTCTGATTCACTGTTTTGTATTTTCTAAAAGGGTTATATGTAATTTGAAAGATAGACCTGCCAAGACGTGAGATCTGTGTTCTCCTTGGTTAGAGCTAACATTTTTGGTGAGGAAAGCACTGCAGGAGCAGGCTGG  Show more... 

Expression

  • Expression in
    Tissues and Cells
    Export
    Organism part Protocol Normalization Expression Raw Data Provider
    0.60214
    0.27361
    0.00000
    0.00000
    0.00000
    0.02259
    0.08853
    0.18989
    0.12895
    4.17073
    3.92724
    4.26338
    0.00000
    21.73991
    0.09227
    0.23236
    0.21063
    0.14322
    0.19116
    • Organism part Protocol Number of cells Article GEO
    Description

Biological Properties

  • General FunctionCatalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans (PubMed:10430883). Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct (PubMed:10430883). May protect against inflammation-associated gastric adenocarcinomas (By similarity). {ECO:0000250|UniProtKB:Q14BT6, ECO:0000269|PubMed:10430883}.
  • GO – Biological Processcarbohydrate metabolic process [GO:0005975]; glycoprotein biosynthetic process [GO:0009101]; negative regulation of epithelial cell proliferation [GO:0050680]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]
  • GO – Cellular ComponentGolgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]
  • GO – Molecular Functionacetylglucosaminyltransferase activity [GO:0008375]; hexosyltransferase activity [GO:0016758]