Description
External Links
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Expression
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Biological Properties

Transcriptome  -  SMDBT000011  ( AADAC )

Description

  • IDSMDBT000011
  • Gene SymbolAADAC
  • Namearylacetamide deacetylase
  • OrganismHomo sapiens (Human)
  • Gene SynonymsCES5A1; DAC
  • ChromosomeGRCh38 chr3:151814008-151828488; hg19 chr3:151531904-151546276
  • Gene Sequence
    AGGTTTACTTTCTGTGTTTCTAGAGACCAAGAAGCGGGACGTTCACCATGGGAAGAAAATCGCTGTACCTTCTGATTGTGGGGATCCTCATAGCATATTATATTTATACGCCTCTCCCAGATAACGTTGAGGAGCCATGGAGAATGATGTGGATAAACGCACATCTGAAAACTATACAAAATTTGGCTAC  Show more... 

Expression

  • Expression in
    Tissues and Cells
    Export
    Organism part Protocol Normalization Expression Raw Data Provider
    0.45641
    2.50297
    0.84417
    0.00000
    0.11551
    0.02571
    0.02239
    0.02998
    0.07628
    4.92968
    4.71242
    4.87910
    0.00000
    16.70937
    0.99319
    1.50356
    0.77146
    2.51798
    0.91874
    • Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Description

Biological Properties

  • General FunctionDisplays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. {ECO:0000269|PubMed:17936933, ECO:0000269|PubMed:19339378, ECO:0000269|PubMed:22207054, ECO:0000269|PubMed:22415931, ECO:0000269|PubMed:23542347}.
  • GO – Biological Processlipid metabolic process [GO:0006629]; positive regulation of triglyceride catabolic process [GO:0010898]; xenobiotic metabolic process [GO:0006805]
  • GO – Cellular Componentendoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]
  • GO – Molecular Functioncatalytic activity [GO:0003824]; deacetylase activity [GO:0019213]; hydrolase activity [GO:0016787]; lipase activity [GO:0016298]; serine hydrolase activity [GO:0017171]; triglyceride lipase activity [GO:0004806]