Description
External Links
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Expression
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Biological Properties

Transcriptome  -  SMDBT001305  ( ATP2A3 )

Description

  • IDSMDBT001305
  • Gene SymbolATP2A3
  • NameATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
  • OrganismHomo sapiens (Human)
  • Gene SynonymsSERCA3
  • ChromosomeGRCh38 chr17:3923869-3964464; hg19 chr17:3827163-3867758
  • Gene Sequence
    ATCCTGGCGCGGGCCGGGGCCGCCGCCGCCACTGCCGTCGGGTAAGGTCCCAGCACGGACATGGCCTCGCGCGGCGCCCGCCCGGGCCCGAGTCCCCCGCGCCCCGCTTTGTAGCCCCCCGGCGGAGAGGCGGCCTCGACGGTGCGGACGGCGCAGACGGCCGGGCGGGCGGCATGGAGGCGGCGCATCT  Show more... 

Expression

  • Expression in
    Tissues and Cells
    Export
    Organism part Protocol Normalization Expression Raw Data Provider
    3.62130
    8.06909
    2.35161
    0.80018
    2.18977
    0.13244
    1.74414
    1.73420
    3.72033
    7.54980
    7.40085
    8.42401
    0.00000
    19.31384
    4.11854
    2.99432
    1.89710
    1.90538
    3.08411
    • Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Description

Biological Properties

  • General FunctionThis magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. {ECO:0000269|PubMed:11956212, ECO:0000269|PubMed:15028735}.
  • GO – Biological Processactivation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium ion transport from cytosol to endoplasmic reticulum [GO:1903515]; cellular calcium ion homeostasis [GO:0006874]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; ion transmembrane transport [GO:0034220]; negative regulation of receptor binding [GO:1900121]; regulation of cardiac conduction [GO:1903779]; transport across blood-brain barrier [GO:0150104]
  • GO – Cellular Componentendoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; organelle membrane [GO:0031090]; platelet dense tubular network membrane [GO:0031095]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]
  • GO – Molecular FunctionATP binding [GO:0005524]; calcium-dependent ATPase activity [GO:0030899]; calcium ion transmembrane transporter activity [GO:0015085]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; metal ion binding [GO:0046872]; P-type calcium transporter activity [GO:0005388]; P-type ion transporter activity [GO:0015662]; transmembrane transporter binding [GO:0044325]