Description
External Links
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Expression
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Biological Properties

Transcriptome  -  SMDBT002373  ( CA4 )

Description

  • IDSMDBT002373
  • Gene SymbolCA4
  • Namecarbonic anhydrase 4
  • OrganismHomo sapiens (Human)
  • Gene SynonymsCAIV; Car4; RP17
  • ChromosomeGRCh38 chr17:60149942-60179021; hg19 chr17:58227334-58256382
  • Gene Sequence
    ACCCGCGGCGGCCTCCTCGGTGCGCGACCCCCGGCTCAGAGGACTCTTTGCTGTCCCGCAAGATGCGGATGCTGCTGGCGCTCCTGGCCCTCTCCGCGGCGCGGCCATCGGCCAGTGCAGAGTCACACTGGTGCTACGAGGTTCAAGCCGAGTCCTCCAACTACCCCTGCTTGGTGCCAGTCAAGTGGGG  Show more... 

Expression

  • Expression in
    Tissues and Cells
    Export
    Organism part Protocol Normalization Expression Raw Data Provider
    3.17413
    2.01588
    0.96293
    9.43183
    35.22366
    0.07517
    84.56753
    168.01184
    78.30790
    8.93419
    9.49293
    9.21734
    0.00000
    5.14400
    0.78950
    0.08558
    0.19623
    0.18105
    0.25426
    • Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Description

Biological Properties

  • General FunctionReversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid. {ECO:0000269|PubMed:15563508}.
  • GO – Biological Processbicarbonate transport [GO:0015701]; one-carbon metabolic process [GO:0006730]
  • GO – Cellular Componentanchored component of external side of plasma membrane [GO:0031362]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]
  • GO – Molecular Functioncarbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]