Description
External Links
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Expression
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Biological Properties

Transcriptome  -  SMDBT002514  ( CAPZB )

Description

  • IDSMDBT002514
  • Gene SymbolCAPZB
  • Namecapping actin protein of muscle Z-line subunit beta
  • OrganismHomo sapiens (Human)
  • Gene SynonymsCAPB; CAPPB; CAPZ
  • ChromosomeGRCh38 chr1:19338775-19485539; hg19 chr1:19665269-19812033
  • Gene Sequence
    ATGTTCACTCCTGGGCACCCGGGGAAGTGGAAGCGCCGGGCCCTGCTGCGGGGGGGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGAGTGATCAGCAGCTGGACTGTGCCTTGGACCTAATGAGGCGCCTGCCTCCCCAGCAAATCGAGAAAAACCTCAGCGACCTGATCGA  Show more... 

Expression

  • Expression in
    Tissues and Cells
    Export
    Organism part Protocol Normalization Expression Raw Data Provider
    197.96249
    118.09687
    88.31337
    15.33516
    31.98952
    114.53283
    54.35027
    64.23845
    67.52591
    12.97849
    13.38672
    13.70113
    22.42234
    92.45545
    173.05114
    28.38046
    29.83307
    20.85934
    23.19190
    • Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Description

Biological Properties

  • General FunctionF-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. {ECO:0000269|PubMed:21834987}.
  • GO – Biological Processactin polymerization or depolymerization [GO:0008154]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; negative regulation of filopodium assembly [GO:0051490]; regulation of cell morphogenesis [GO:0022604]; regulation of lamellipodium assembly [GO:0010591]
  • GO – Cellular Componentactin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cortical cytoskeleton [GO:0030863]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; lamellipodium [GO:0030027]; membrane [GO:0016020]; postsynaptic density [GO:0014069]; sarcomere [GO:0030017]; Schaffer collateral - CA1 synapse [GO:0098685]; sperm connecting piece [GO:0097224]; WASH complex [GO:0071203]
  • GO – Molecular Functionactin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]