Description
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Expression
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Biological Properties

Transcriptome  -  SMDBT013452  ( PGP )

Description

  • IDSMDBT013452
  • Gene SymbolPGP
  • Namephosphoglycolate phosphatase
  • OrganismHomo sapiens (Human)
  • Gene SynonymsAUM; G3PP; PGPase
  • ChromosomeGRCh38 chr16:2211593-2214840; hg19 chr16:2261594-2264841
  • Gene Sequence
    GAGGGCGCCGCGGCGGGCGGCTGCGAGGAGCGGCCGGCGGGCGGCGGCGGCCGGCGGGCGGCGATGGCGGCGGCGGAGGCCGGTGGCGACGACGCCCGCTGCGTGCGGCTGAGCGCCGAGCGGGCACAGGCGCTGCTGGCCGACGTGGACACGCTGCTGTTCGACTGCGACGGCGTGCTGTGGCGCGGGG  Show more... 

Expression

  • Expression in
    Tissues and Cells
    Export
    Organism part Protocol Normalization Expression Raw Data Provider
    50.40101
    54.23439
    27.81240
    12.94530
    29.56905
    13.07635
    11.03373
    16.51526
    7.81592
    8.45950
    8.05272
    8.14126
    38.04774
    48.39274
    21.69959
    10.86324
    7.68577
    16.24556
    19.29706
  • Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Description

Biological Properties

  • General FunctionGlycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity). {ECO:0000250|UniProtKB:Q8CHP8, ECO:0000269|PubMed:26755581}.
  • GO – Biological Processdephosphorylation [GO:0016311]; glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine dephosphorylation [GO:0035335]
  • GO – Cellular Componentcytoplasm [GO:0005737]
  • GO – Molecular Functionglycerol-1-phosphatase activity [GO:0000121]; glycerol-3-phosphatase activity [GO:0043136]; magnesium ion binding [GO:0000287]; nucleotide phosphatase activity, acting on free nucleotides [GO:0098519]; phosphatase activity [GO:0016791]; phosphoglycolate phosphatase activity [GO:0008967]; protein tyrosine phosphatase activity [GO:0004725]