Description
External Links
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Expression
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Biological Properties

Transcriptome  -  SMDBT019319  ( TUBB8 )

Description

  • IDSMDBT019319
  • Gene SymbolTUBB8
  • Nametubulin beta 8 class VIII
  • OrganismHomo sapiens (Human)
  • Gene SynonymsOOMD; OOMD2; bA631M21.2
  • ChromosomeGRCh38 chr10:46437-49504; hg19 chr10:92828-95178
  • Gene Sequence
    ATGAGGGAGATCGTGCTCACGCAGATCGGGCAGTGCGGGAATCAGATCGGCGCCAAGTTCTGGGAGGTGATCTCTGATGAACATGCCATCGACTCCGCTGGCACCTACCACGGGGACAGCCACCTGCAGCTGGAGCGCATCAACGTGTACTACAACGAGGCCAGCGGTGGCAGGTACGTGCCCCGCGCTG  Show more... 

Expression

  • Expression in
    Tissues and Cells
    Export
    Organism part Protocol Normalization Expression Raw Data Provider
    5.70436
    2.07219
    1.47630
    0.17779
    0.09267
    0.18960
    0.17989
    0.20850
    0.15157
    5.87528
    5.40977
    6.01136
    107.26721
    3.00078
    0.55353
    0.29514
    0.37788
    0.36345
    • Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Organism part Protocol Number of cells Article GEO
    Description

Biological Properties

  • General FunctionTubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). TUBB8 has a key role in meiotic spindle assembly and oocyte maturation (PubMed:26789871). {ECO:0000250, ECO:0000269|PubMed:26789871}.
  • GO – Biological Processmicrotubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; spindle assembly involved in female meiosis [GO:0007056]
  • GO – Cellular Componentcytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]
  • GO – Molecular FunctionGTPase activity [GO:0003924]; GTP binding [GO:0005525]; structural constituent of cytoskeleton [GO:0005200]