Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Acromegaly
ADR ID BADD_A00065
ADR Hierarchy
05      Endocrine disorders
05.03      Hypothalamus and pituitary gland disorders
05.03.01      Anterior pituitary hyperfunction
05.03.01.005      Acromegaly
14      Metabolism and nutrition disorders
14.11      Metabolism disorders NEC
14.11.01      Metabolic disorders NEC
14.11.01.029      Acromegaly
24      Vascular disorders
24.08      Vascular hypertensive disorders
24.08.04      Endocrine and metabolic secondary hypertension
24.08.04.004      Acromegaly
15      Musculoskeletal and connective tissue disorders
15.03      Musculoskeletal and connective tissue disorders NEC
15.03.05      Musculoskeletal and connective tissue conditions NEC
15.03.05.002      Acromegaly
Description A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80) [MeSH]
MedDRA Code 10000599
MeSH ID D000172
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acromegaly | Acromegaly and gigantism | Somatotropin Hypersecretion Syndrome (Acromegaly) | Hypersecretion Syndrome, Somatotropin (Acromegaly) | Hypersecretion Syndromes, Somatotropin (Acromegaly) | Somatotropin Hypersecretion Syndromes (Acromegaly) | Syndrome, Somatotropin Hypersecretion (Acromegaly) | Syndromes, Somatotropin Hypersecretion (Acromegaly) | Inappropriate GH Secretion Syndrome (Acromegaly) | Inappropriate Growth Hormone Secretion Syndrome (Acromegaly)
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00305Bromocriptine mesylate--
BADD_D00329Cabergoline0.019218%
BADD_D01951Risperidone0.000242%
BADD_D02412Octreotide0.000186%
The 1th Page    1    Total 1 Pages