Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Actinic keratosis
ADR ID BADD_A00066
ADR Hierarchy
23      Skin and subcutaneous tissue disorders
23.01      Cornification and dystrophic skin disorders
23.01.06      Skin preneoplastic conditions NEC
23.01.06.001      Actinic keratosis
Description White or pink lesions on the arms, hands, face, or scalp that arise from sun-induced DNA DAMAGE to KERATINOCYTES in exposed areas. They are considered precursor lesions to superficial SQUAMOUS CELL CARCINOMA. [MeSH]
MedDRA Code 10000614
MeSH ID D055623
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Actinic keratosis | Senile keratosis | Solar keratosis | Hypertrophic actinic keratosis | Pigmented actinic keratosis | Bowenoid actinic keratosis | Acantholytic actinic keratosis | Keratosis, Actinic | Actinic Keratoses | Keratoses, Actinic | Actinic Keratosis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000418%
BADD_D00195Azathioprine0.000783%
BADD_D00277Bisoprolol0.000628%
BADD_D00349Capecitabine0.000884%
BADD_D00364Carboplatin0.000112%
BADD_D00566Dabrafenib0.000112%
BADD_D00567Dabrafenib mesylate--
BADD_D00723Doxorubicin0.000112%
BADD_D00768Enalaprilat0.003039%
BADD_D00898Finasteride0.000256%
BADD_D01083Hydrochlorothiazide0.000066%
BADD_D01110Hydroxyurea0.001063%
BADD_D01119Ibrutinib0.000280%
BADD_D01142Imiquimod0.000439%
BADD_D01401Metformin0.000016%
BADD_D01445Metoprolol0.000020%
BADD_D01831Prednisolone0.000035%
BADD_D01909Ramipril0.000233%
BADD_D01966Ropinirole--
BADD_D02018Sildenafil0.000107%
BADD_D02029Sitagliptin0.000117%
BADD_D02053Sofosbuvir0.000960%
BADD_D02105Tacrolimus0.003119%
BADD_D02106Tadalafil0.000293%
BADD_D02257Trametinib--
BADD_D02258Trametinib dimethyl sulfoxide--
BADD_D02331Valsartan0.000053%
BADD_D02344Vemurafenib0.000616%
BADD_D02365Vismodegib0.000392%
BADD_D02369Voriconazole0.111524%
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