Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Acute promyelocytic leukaemia
ADR ID BADD_A00082
ADR Hierarchy
01      Blood and lymphatic system disorders
01.10      Leukaemias
01.10.05      Leukaemias acute myeloid
01.10.05.003      Acute promyelocytic leukaemia
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.01      Leukaemias
16.01.05      Leukaemias acute myeloid
16.01.05.003      Acute promyelocytic leukaemia
Description An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION. [MeSH]
MedDRA Code 10001019
MeSH ID D015473
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute promyelocytic leukaemia | Acute promyelocytic leukemia | Leukemia, Promyelocytic, Acute | Leukemia, Acute Promyelocytic | Leukemia, Myeloid, Acute, M3 | M3 ANLL | ANLL, M3 | Myeloid Leukemia, Acute, M3 | Progranulocytic Leukemia | Promyelocytic Leukemia, Acute | AML M3 | Acute Promyelocytic Leukemia | Acute Promyelocytic Leukemias | Leukemia, Progranulocytic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00142Anastrozole0.000159%
BADD_D00169Arsenic trioxide0.000112%
BADD_D00195Azathioprine0.000470%
BADD_D00349Capecitabine0.000224%
BADD_D00364Carboplatin0.000168%
BADD_D00474Cisplatin0.000112%
BADD_D00511Clozapine0.001223%
BADD_D00568Dacarbazine0.000112%
BADD_D00723Doxorubicin0.000112%
BADD_D00775Enzalutamide0.000501%
BADD_D00854Etoposide0.000224%
BADD_D00931Fluorouracil0.000276%
BADD_D01133Ifosfamide--
BADD_D01136Imatinib0.000280%
BADD_D01281Levonorgestrel0.000473%
BADD_D01376Melphalan0.000224%
BADD_D01401Metformin0.000005%
BADD_D01480Mitoxantrone0.000112%
BADD_D01567Nilotinib0.000112%
BADD_D01609Omacetaxine mepesuccinate0.000112%
BADD_D01629Osimertinib0.000168%
BADD_D01834Prednisone0.000018%
BADD_D02270Tretinoin0.000107%
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