Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Atrial flutter
ADR ID BADD_A00373
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.03      Supraventricular arrhythmias
02.03.03.003      Atrial flutter
Description A disorder characterized by a dysrhythmia with organized rhythmic atrial contractions with a rate of 200-300 beats per minute. The rhythm disturbance originates in the atria. [CTCAE] Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES). [MeSH]
MedDRA Code 10003662
MeSH ID D001282
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Atrial flutter | Flutter atrial | Paroxysmal atrial flutter | Atrial flutter with 1:1 atrioventricular conduction | Atrial flutter with rapid ventricular response | Atrial flutter with slow ventricular response | Typical atrial flutter | Atypical atrial flutter | Atrial Flutter | Atrial Flutters | Flutter, Atrial | Flutters, Atrial | Auricular Flutter | Auricular Flutters | Flutter, Auricular | Flutters, Auricular
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00971Fosphenytoin sodium--
BADD_D01119Ibrutinib0.002664%
BADD_D01133Ifosfamide--
BADD_D01135Iloprost0.000082%
BADD_D01149Indapamide--
BADD_D01217Itraconazole0.004008%
BADD_D01218Ivabradine0.000228%
BADD_D01222Ixabepilone--
BADD_D01238Lacosamide0.005851%
BADD_D01253Lenalidomide0.006606%
BADD_D01285Levothyroxine0.000022%
BADD_D01300Lisinopril--
BADD_D01336Macitentan0.001227%
BADD_D01445Metoprolol0.000093%
BADD_D01473Minoxidil0.000701%
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01507Mycophenolate mofetil--
BADD_D01508Mycophenolic acid--
BADD_D01535Naratriptan--
BADD_D01567Nilotinib0.000336%
BADD_D01583Norepinephrine0.000085%
BADD_D01620Oprelvekin--
BADD_D01661Pamidronate disodium--
BADD_D01662Pamidronic acid--
BADD_D01668Pantoprazole0.000025%
BADD_D01676Paricalcitol--
BADD_D01765Phenytoin--
BADD_D01777Pioglitazone0.000086%
BADD_D01799Ponatinib--
BADD_D01803Porfimer sodium--
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