Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Atrioventricular block first degree
ADR ID BADD_A00378
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.01      Cardiac conduction disorders
02.03.01.004      Atrioventricular block first degree
Description A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds. [CTCAE]
MedDRA Code 10003674
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
1st degree heart block | Atrioventricular block first degree | Atrioventricular conduction time prolonged | AV block first degree | First degree atrioventricular block | Heart block 1st degree | Heart block AV first degree | Heart block first degree
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01818Pramipexole dihydrochloride--
BADD_D01835Pregabalin--
BADD_D01856Propafenone0.001463%
BADD_D01857Propafenone hydrochloride--
BADD_D01864Propofol0.000179%
BADD_D01867Propranolol0.000294%
BADD_D01888Quetiapine--
BADD_D01889Quetiapine fumarate--
BADD_D01921Regadenoson0.000169%
BADD_D01923Remifentanil hydrochloride--
BADD_D01951Risperidone--
BADD_D01952Ritonavir--
BADD_D01977Rufinamide--
BADD_D02002Selegiline--
BADD_D02026Simvastatin0.000011%
BADD_D02031Sitaxentan--
BADD_D02060Sotalol--
BADD_D02062Sparfloxacin--
BADD_D02066Spironolactone0.000055%
BADD_D02214Ticagrelor0.000598%
BADD_D02217Tigecycline--
BADD_D02247Topiramate0.000101%
BADD_D02259Trandolapril--
BADD_D02260Trandolaprilat--
BADD_D02346Venlafaxine--
BADD_D02348Verapamil0.000346%
BADD_D02351Vernakalant hydrochloride--
BADD_D02389Ziprasidone hydrochloride--
BADD_D02391Ziprasidone mesylate--
BADD_D02412Octreotide0.000186%
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ADReCS-Target
ADR Term Drug Name Target