Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Blood insulin
ADR ID BADD_A00565
ADR Hierarchy
13      Investigations
13.10      Endocrine investigations (incl sex hormones)
13.10.02      Gastrointestinal, pancreatic and APUD hormone analyses
13.10.02.010      Blood insulin
Description A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). [MeSH]
MedDRA Code 10005605
MeSH ID D007328
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Blood insulin | Insulin | Plasma insulin | Serum insulin | Immunoreactive insulin | Insulin, Regular | Regular Insulin | Soluble Insulin | Insulin, Soluble | Insulin A Chain | Sodium Insulin | Insulin, Sodium | Novolin | Iletin | Insulin B Chain | Chain, Insulin B
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01165Insulin lispro--
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