Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cardiac failure congestive
ADR ID BADD_A00775
ADR Hierarchy
02      Cardiac disorders
02.05      Heart failures
02.05.01      Heart failures NEC
02.05.01.002      Cardiac failure congestive
Description A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. | Heart failure involving the RIGHT VENTRICLE. | Heart failure caused by dysfunction of the MYOCARDIUM, leading to defective cardiac emptying (contraction) or filling (relaxation). | Heart failure accompanied by EDEMA, such as swelling of the legs and ankles and congestion in the lungs. | Heart failure involving the LEFT VENTRICLE. [MeSH]
MedDRA Code 10007559
MeSH ID D006333
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bi-ventricular failure | Cardiac failure congestive | Cardiac failure, congestive | CCF | CHF | Congestive cardiac failure | Congestive heart failure | Failure heart congestive | Heart failure, congestive | Rheumatic heart failure (congestive) | Congestive cardiac failure aggravated | Congestive cardiac failure aggr. | Congestive heart failure with acute exacerbation | Combined congestive cardiac failure | Heart Failure | Cardiac Failure | Heart Decompensation | Decompensation, Heart | Heart Failure, Right-Sided | Heart Failure, Right Sided | Right-Sided Heart Failure | Right Sided Heart Failure | Myocardial Failure | Congestive Heart Failure | Heart Failure, Congestive | Heart Failure, Left-Sided | Heart Failure, Left Sided | Left-Sided Heart Failure | Left Sided Heart Failure
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01156Indomethacin--
BADD_D01166Interferon alfa-2a--
BADD_D01167Interferon alfa-2b--
BADD_D01169Interferon beta-1a--
BADD_D01182Iopromide--
BADD_D01194Irbesartan0.000252%
BADD_D01197Iron--
BADD_D01199Iron sucrose--
BADD_D01217Itraconazole0.024051%
BADD_D01218Ivabradine0.000127%
BADD_D01231Ketoprofen--
BADD_D01232Ketorolac--
BADD_D01233Ketorolac tromethamine--
BADD_D01236Labetalol0.000163%
BADD_D01253Lenalidomide0.061460%
BADD_D01254Lenvatinib--
BADD_D01260Leuprolide acetate--
BADD_D01261Leuprolide monoacetate--
BADD_D01267Levobunolol--
BADD_D01268Levobunolol hydrochloride--
BADD_D01285Levothyroxine--
BADD_D01292Linagliptin--
BADD_D01295Linezolid--
BADD_D01296Liothyronine--
BADD_D01300Lisinopril0.000132%
BADD_D01311Lomitapide0.000032%
BADD_D01319Lorcaserin hydrochloride--
BADD_D01322Losartan0.000084%
BADD_D01325Lovastatin--
BADD_D01336Macitentan0.012022%
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