Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Carotid artery stenosis
ADR ID BADD_A00804
ADR Hierarchy
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.02      Central nervous system vascular disorders NEC
17.08.02.001      Carotid artery stenosis
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.06      Cerebrovascular and spinal necrosis and vascular insufficiency
24.04.06.001      Carotid artery stenosis
Description Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3) [MeSH]
MedDRA Code 10007687
MeSH ID D016893
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Carotid artery stenosis | Internal carotid artery stenosis | External carotid artery stenosis | Carotid Stenosis | Carotid Stenoses | Stenoses, Carotid | Stenosis, Carotid | Carotid Artery Narrowing | Artery Narrowing, Carotid | Artery Narrowings, Carotid | Carotid Artery Narrowings | Narrowing, Carotid Artery | Narrowings, Carotid Artery | Carotid Artery Stenosis | Artery Stenoses, Carotid | Artery Stenosis, Carotid | Carotid Artery Stenoses | Stenoses, Carotid Artery | Stenosis, Carotid Artery | Internal Carotid Artery Stenosis | Common Carotid Artery Stenosis | Stenosis, Common Carotid Artery | External Carotid Artery Stenosis | Stenosis, External Carotid Artery | Carotid Artery Plaque | Artery Plaque, Carotid | Artery Plaques, Carotid | Carotid Artery Plaques | Plaque, Carotid Artery | Plaques, Carotid Artery | Carotid Ulcer | Carotid Ulcers | Ulcer, Carotid | Ulcers, Carotid | Ulcerating Plaque, Carotid Artery | Plaque, Ulcerating, Carotid Artery | Carotid Artery Ulcerating Plaque
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00033Acetylsalicylic acid0.000044%
BADD_D00066Alendronic acid0.000330%
BADD_D00121Amlodipine0.000006%
BADD_D00151Apixaban0.000347%
BADD_D00178Atenolol0.000019%
BADD_D00194Azacitidine0.000112%
BADD_D00364Carboplatin0.000358%
BADD_D00410Celecoxib0.000075%
BADD_D00504Clopidogrel0.000043%
BADD_D00563Dabigatran0.002006%
BADD_D00680Dimethyl fumarate0.000600%
BADD_D00864Ezetimibe0.000094%
BADD_D00898Finasteride0.000067%
BADD_D01119Ibrutinib0.000112%
BADD_D01242Lamivudine0.002024%
BADD_D01260Leuprolide acetate0.001434%
BADD_D01401Metformin0.000005%
BADD_D01445Metoprolol0.000007%
BADD_D01567Nilotinib0.004141%
BADD_D01799Ponatinib0.000168%
BADD_D01954Rivaroxaban0.000285%
BADD_D01970Rosiglitazone maleate--
BADD_D02018Sildenafil0.000107%
BADD_D02029Sitagliptin0.000053%
BADD_D02107Tafamidis0.001346%
BADD_D02170Testosterone0.000318%
BADD_D02325Valdecoxib--
BADD_D02331Valsartan0.000106%
BADD_D02407Upadacitinib0.000362%
BADD_D02464Fingolimod0.000362%
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