Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cerebral ischaemia
ADR ID BADD_A00846
ADR Hierarchy
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.01      Central nervous system haemorrhages and cerebrovascular accidents
17.08.01.005      Cerebral ischaemia
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.06      Cerebrovascular and spinal necrosis and vascular insufficiency
24.04.06.003      Cerebral ischaemia
Description Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION. [MeSH]
MedDRA Code 10008120
MeSH ID D002545
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cerebral ischaemia | Cerebral ischemia | Ischemia cerebral | Ischemia cerebrovascular | Other generalized ischaemic cerebrovascular disease | Other generalized ischemic cerebrovascular disease | Ischaemia cerebral | Ischaemia cerebrovascular | Chronic cerebral ischemia | Chronic cerebral ischaemia | Focal cerebral ischemia | Focal cerebral ischaemia | Brain Ischemia | Brain Ischemias | Ischemia, Brain | Ischemic Encephalopathy | Encephalopathy, Ischemic | Ischemic Encephalopathies | Cerebral Ischemia | Cerebral Ischemias | Ischemias, Cerebral | Ischemia, Cerebral
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01923Remifentanil hydrochloride--
BADD_D01933Ribavirin0.003956%
BADD_D01942Riluzole--
BADD_D01951Risperidone0.000182%
BADD_D01952Ritonavir--
BADD_D01954Rivaroxaban0.002502%
BADD_D01971Rosuvastatin0.000017%
BADD_D02002Selegiline--
BADD_D02010Sertraline0.000032%
BADD_D02016Sibutramine--
BADD_D02018Sildenafil0.000107%
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02100Sunitinib0.000168%
BADD_D02105Tacrolimus0.000446%
BADD_D02150Temozolomide--
BADD_D02170Testosterone0.000227%
BADD_D02192Thalidomide--
BADD_D02210Tiagabine--
BADD_D02211Tiagabine hydrochloride--
BADD_D02219Timolol--
BADD_D02241Tolcapone--
BADD_D02334Vandetanib--
BADD_D02345Venetoclax0.000112%
BADD_D02346Venlafaxine--
BADD_D02369Voriconazole--
BADD_D02373Warfarin0.000112%
BADD_D02379Zaleplon--
BADD_D02393Zolmitriptan--
BADD_D02469Edoxaban0.000123%
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