Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cholestasis
ADR ID BADD_A00906
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.01      Cholestasis and jaundice
09.01.01.001      Cholestasis
Description Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS). [MeSH]
MedDRA Code 10008635
MeSH ID D002779
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Biliary stasis | Cholestasis | Cholestasis extrahepatic | Cholestasis intrahepatic | Cholestatic liver disease | Liver cholestasis | Pure intrahepatic cholestasis | Cholestatic hepatic disorder | Anicteric cholestasis | Cholestases | Biliary Stasis | Biliary Stases | Stases, Biliary | Stasis, Biliary | Bile Duct Obstruction | Bile Duct Obstructions | Duct Obstruction, Bile | Duct Obstructions, Bile | Obstruction, Bile Duct | Obstructions, Bile Duct
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01848Prochlorperazine--
BADD_D01849Prochlorperazine edisylate--
BADD_D01850Prochlorperazine maleate--
BADD_D01852Progesterone0.000125%
BADD_D01856Propafenone0.000836%
BADD_D01857Propafenone hydrochloride--
BADD_D01864Propofol0.000179%
BADD_D01867Propranolol0.000134%
BADD_D01880Pyrazinamide0.001027%
BADD_D01905Raltegravir0.002472%
BADD_D01909Ramipril0.000466%
BADD_D01922Regorafenib0.000560%
BADD_D01933Ribavirin0.025713%
BADD_D01936Rifampicin0.003733%
BADD_D01938Rifaximin0.000322%
BADD_D01951Risperidone0.000909%
BADD_D01954Rivaroxaban--
BADD_D01971Rosuvastatin0.000086%
BADD_D02010Sertraline0.000331%
BADD_D02026Simvastatin0.000044%
BADD_D02029Sitagliptin0.000265%
BADD_D02031Sitaxentan--
BADD_D02053Sofosbuvir0.000847%
BADD_D02093Sulfasalazine--
BADD_D02097Sulindac--
BADD_D02105Tacrolimus0.005495%
BADD_D02111Tamoxifen--
BADD_D02112Tamoxifen citrate--
BADD_D02113Tamsulosin0.000019%
BADD_D02137Teduglutide--
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