Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Circadian rhythm sleep disorder
ADR ID BADD_A00939
ADR Hierarchy
17      Nervous system disorders
17.15      Sleep disturbances (incl subtypes)
17.15.06      Disturbances in sleep phase rhythm
17.15.06.002      Circadian rhythm sleep disorder
19      Psychiatric disorders
19.02      Sleep disorders and disturbances
19.02.06      Sleep phase rhythm disturbances
19.02.06.002      Circadian rhythm sleep disorder
Description A chronobiologic disorder resulting from rapid travel across a number of time zones, characterized by insomnia or hypersomnolence, fatigue, behavioral symptoms, headaches, and gastrointestinal disturbances. (From Cooper, Sleep, 1994, pp593-8) [MeSH]
MedDRA Code 10009191
MeSH ID D020179; D020178
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Circadian dysrhythmia | Circadian rhythm sleep disorder | Jet lag | Sleep-wake schedule disorder | Jet Lag Syndrome | Jet Lag Syndromes | Time Zone Change Syndrome | Time Zone Syndrome | Time Zone Syndromes | Jet Lag | Jet Lags | Lag, Jet | Lags, Jet
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam0.000049%
BADD_D00732Droxidopa0.000186%
BADD_D00802Ertapenem0.000049%
BADD_D00898Finasteride0.000243%
BADD_D01498Morphine0.000412%
BADD_D01599Olanzapine0.000526%
BADD_D02047Sodium oxybate0.000590%
BADD_D02236Tofacitinib0.000820%
BADD_D02247Topiramate--
BADD_D02337Varenicline--
BADD_D02451Pimavanserin0.000353%
BADD_D02464Fingolimod0.000530%
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