Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00759Eltrombopag--
BADD_D00761Eluxadoline0.002101%
BADD_D00767Enalapril maleate--
BADD_D00768Enalaprilat--
BADD_D00769Encainide hydrochloride--
BADD_D00771Enfuvirtide--
BADD_D00773Entacapone0.004115%
BADD_D00775Enzalutamide0.032867%
BADD_D00784Epirubicin0.000112%
BADD_D00785Epirubicin hydrochloride--
BADD_D00786Eplerenone--
BADD_D00788Epoprostenol--
BADD_D00790Eprosartan--
BADD_D00791Eprosartan mesylate--
BADD_D00794Ergocalciferol0.002530%
BADD_D00798Eribulin--
BADD_D00799Eribulin mesylate--
BADD_D00800Erlotinib--
BADD_D00801Erlotinib hydrochloride--
BADD_D00802Ertapenem--
BADD_D00803Ertapenem sodium--
BADD_D00809Escitalopram--
BADD_D00810Escitalopram oxalate--
BADD_D00811Eslicarbazepine--
BADD_D00812Eslicarbazepine acetate--
BADD_D00813Esmolol--
BADD_D00814Esmolol hydrochloride--
BADD_D00815Esomeprazole--
BADD_D00816Esomeprazole magnesium--
BADD_D00817Esomeprazole sodium--
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