Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01053Halofantrine hydrochloride--
BADD_D01054Haloperidol0.001015%
BADD_D01055Haloperidol decanoate--
BADD_D01056Haloperidol lactate--
BADD_D01064Hepatitis b vaccine (recombinant)--
BADD_D01071Histamine--
BADD_D01073Histrelin--
BADD_D01081Hydralazine--
BADD_D01082Hydralazine hydrochloride--
BADD_D01083Hydrochlorothiazide--
BADD_D01084Hydrocodone--
BADD_D01086Hydrocortisone0.000092%
BADD_D01087Hydrocortisone acetate--
BADD_D01093Hydroflumethiazide--
BADD_D01096Hydromorphone--
BADD_D01102Hydroxybutanoic acid--
BADD_D01110Hydroxyurea--
BADD_D01111Hydroxyzine--
BADD_D01114Hyoscyamine--
BADD_D01115Hyoscyamine sulfate--
BADD_D01116Ibandronate sodium--
BADD_D01117Ibandronic acid--
BADD_D01119Ibrutinib--
BADD_D01120Ibuprofen--
BADD_D01124Icodextrin--
BADD_D01126Icosapent ethyl-
BADD_D01129Idarucizumab--
BADD_D01133Ifosfamide--
BADD_D01134Iloperidone0.000287%
BADD_D01136Imatinib--
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