Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00161Argatroban--
BADD_D00165Aripiprazole--
BADD_D00167Armodafinil--
BADD_D00168Arsenic--
BADD_D00169Arsenic trioxide--
BADD_D00170Articaine hydrochloride--
BADD_D00171Ascorbic acid0.000991%
BADD_D00172Asenapine--
BADD_D00173Asenapine maleate--
BADD_D00176Atazanavir--
BADD_D00178Atenolol0.000192%
BADD_D00179Atezolizumab--
BADD_D00180Atomoxetine0.001136%
BADD_D00181Atomoxetine hydrochloride--
BADD_D00182Atorvastatin calcium--
BADD_D00186Atovaquone--
BADD_D00189Atropine--
BADD_D00190Atropine sulfate--
BADD_D00191Auranofin--
BADD_D00192Avanafil--
BADD_D00193Axitinib0.019095%
BADD_D00194Azacitidine0.005384%
BADD_D00195Azathioprine--
BADD_D00198Azelastine--
BADD_D00203Azithromycin--
BADD_D00204Azithromycin dihydrate--
BADD_D00205Azithromycin monohydrate--
BADD_D00209Baclofen--
BADD_D00210Balsalazide--
BADD_D00211Balsalazide disodium--
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