Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00214Basiliximab--
BADD_D00221Bedaquiline0.002259%
BADD_D00223Belatacept--
BADD_D00225Belinostat0.000504%
BADD_D00227Benazepril--
BADD_D00228Benazepril hydrochloride--
BADD_D00229Benazeprilat--
BADD_D00230Bendamustine--
BADD_D00231Bendamustine hydrochloride--
BADD_D00232Bendroflumethiazide--
BADD_D00235Benzalkonium chloride--
BADD_D00236Benzatropine--
BADD_D00240Benzonatate--
BADD_D00244Benztropine--
BADD_D00245Benztropine mesylate--
BADD_D00254Bepridil--
BADD_D00263Betaxolol--
BADD_D00268Bevacizumab--
BADD_D00269Bexarotene0.000112%
BADD_D00270Bezafibrate--
BADD_D00271Bicalutamide--
BADD_D00275Biperiden hydrochloride--
BADD_D00276Bisacodyl--
BADD_D00277Bisoprolol--
BADD_D00278Bisoprolol fumarate--
BADD_D00282Blinatumomab--
BADD_D00283Boceprevir--
BADD_D00284Bortezomib0.003783%
BADD_D00285Bosentan--
BADD_D00286Bosutinib0.005496%
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