Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cyanosis
ADR ID BADD_A01135
ADR Hierarchy
02      Cardiac disorders
02.01      Cardiac disorder signs and symptoms
02.01.02      Cardiac signs and symptoms NEC
02.01.02.002      Cyanosis
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.02      Conditions associated with abnormal gas exchange
22.02.02.007      Cyanosis
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.01      Peripheral vascular disorders NEC
24.03.01.007      Cyanosis
Description A disorder characterized by a bluish discoloration of the skin and/or mucous membranes. [CTCAE] A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule. [MeSH]
MedDRA Code 10011703
MeSH ID D003490
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acrocyanosis | Blue lips | Cyanosed | Cyanosis | Cyanosis NOS | Cyanosis of lip | Cyanosis peripheral | Cyanotic | Lips cyanosed | Nails cyanosed | Circumoral cyanosis | Cyanosis aggravated | Cyanoses
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00029Acetyl sulfisoxazole--
BADD_D00036Acitretin--
BADD_D00071Alglucosidase alfa--
BADD_D00085Alprazolam0.001045%
BADD_D00100Ambrisentan0.002887%
BADD_D00115Amiodarone0.000893%
BADD_D00121Amlodipine0.000008%
BADD_D00129Amoxicillin0.000071%
BADD_D00132Amphotericin b--
BADD_D00147Antihemophilic factor (recombinant)--
BADD_D00150Antivenin (micrurus fulvius)--
BADD_D00151Apixaban--
BADD_D00165Aripiprazole0.001526%
BADD_D00178Atenolol0.000222%
BADD_D00189Atropine--
BADD_D00195Azathioprine0.001436%
BADD_D00203Azithromycin0.000038%
BADD_D00209Baclofen0.000842%
BADD_D00213Barium sulfate--
BADD_D00237Benzocaine--
BADD_D00272Bicisate dihydrochloride--
BADD_D00277Bisoprolol0.000525%
BADD_D00285Bosentan0.003130%
BADD_D00289Botulinum neurotoxin a/b immune globulin (human)--
BADD_D00294Brimonidine0.000719%
BADD_D00306Budesonide0.002031%
BADD_D00342Calfactant-
BADD_D00349Capecitabine--
BADD_D00354Captopril0.002235%
BADD_D00356Carbamazepine0.002526%
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