Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Deafness neurosensory
ADR ID BADD_A01158
ADR Hierarchy
04      Ear and labyrinth disorders
04.02      Hearing disorders
04.02.01      Hearing losses
04.02.01.002      Deafness neurosensory
17      Nervous system disorders
17.04      Cranial nerve disorders (excl neoplasms)
17.04.07      Auditory nerve disorders
17.04.07.001      Deafness neurosensory
Description Hearing loss due to disease of the AUDITORY PATHWAYS (in the CENTRAL NERVOUS SYSTEM) which originate in the COCHLEAR NUCLEI of the PONS and then ascend bilaterally to the MIDBRAIN, the THALAMUS, and then the AUDITORY CORTEX in the TEMPORAL LOBE. Bilateral lesions of the auditory pathways are usually required to cause central hearing loss. Cortical deafness refers to loss of hearing due to bilateral auditory cortex lesions. Unilateral BRAIN STEM lesions involving the cochlear nuclei may result in unilateral hearing loss. [MeSH]
MedDRA Code 10011891
MeSH ID D006313; D006319
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Central hearing loss | Cochlear function disorder | Cochlear nerve damage | Cochlear nerve deafness | Deafness labyrinthine | Deafness nerve | Deafness nerve type | Deafness neurosensory | High tone sensorineural hearing loss | Nerve deafness | Neural deafness | Neural hearing loss | Neuro sensory deafness | Perceptive deafness | Sensorineural deafness | Sensorineural hearing loss | Sensorineural hearing loss of combined types | Sensorineural hearing loss, unspecified | Sensory hearing loss | Low tone sensorineural hearing loss | Hearing Loss, Central | Central Hearing Loss | Cortical Deafness | Deafness, Cortical
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02373Warfarin0.000098%
BADD_D02407Upadacitinib0.000241%
BADD_D02436Atorvastatin0.000005%
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