Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Dementia
ADR ID BADD_A01187
ADR Hierarchy
17      Nervous system disorders
17.03      Mental impairment disorders
17.03.01      Dementia (excl Alzheimer's type)
17.03.01.001      Dementia
19      Psychiatric disorders
19.20      Dementia and amnestic conditions
19.20.02      Dementia NEC
19.20.02.001      Dementia
Description An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness. [MeSH]
MedDRA Code 10012267
MeSH ID D003704
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Amentia | Brain failure, chronic | Brain syndrome chronic | Chronic brain failure | Chronic brain syndrome | Demented | Dementia | Dementia acquired | Dementia aggravated | Dementia due to Creutzfeldt-Jacob disease | Dementia due to Creutzfeld-Jakob disease | Dementia due to general medical condition | Dementia due to head trauma | Dementia due to Huntington's disease | Dementia due to Jakob's disease | Dementia due to multiple aetiologies | Dementia due to multiple etiologies | Dementia due to other general medical condition | Dementia due to other general medical conditions | Dementia due to Parkinson's disease | Dementia in conditions classified elsewhere | Dementia NOS | Dementia NOS aggravated | Disorder brain (chronic) | Drug-induced dementia | Mental disorder post brain damage | Post-traumatic dementia | Secondary dementia | Syndrome brain chronic | Toxic dementia | Major neurocognitive disorder | Dementias | Amentias | Senile Paranoid Dementia | Dementias, Senile Paranoid | Paranoid Dementia, Senile | Paranoid Dementias, Senile | Senile Paranoid Dementias | Familial Dementia | Dementia, Familial | Dementias, Familial | Familial Dementias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00464Cidofovir dihydrate--
BADD_D00471Ciprofloxacin--
BADD_D00475Citalopram0.000029%
BADD_D00504Clopidogrel0.000096%
BADD_D00511Clozapine0.068358%
BADD_D00528Conjugated estrogens--
BADD_D00551Cyclosporine0.000796%
BADD_D00589Dasatinib--
BADD_D00621Desvenlafaxine0.000535%
BADD_D00648Diazepam0.000176%
BADD_D00667Difluprednate0.000210%
BADD_D00668Digoxin0.000232%
BADD_D00680Dimethyl fumarate0.009962%
BADD_D00686Diphenhydramine0.000672%
BADD_D00696Divalproex sodium--
BADD_D00706Donepezil0.001036%
BADD_D00707Donepezil hydrochloride--
BADD_D00732Droxidopa0.000846%
BADD_D00736Dutasteride0.000455%
BADD_D00755Eletriptan--
BADD_D00756Eletriptan hydrobromide--
BADD_D00759Eltrombopag0.001600%
BADD_D00768Enalaprilat0.007092%
BADD_D00773Entacapone0.013718%
BADD_D00774Entecavir0.004903%
BADD_D00775Enzalutamide0.006006%
BADD_D00786Eplerenone0.007424%
BADD_D00788Epoprostenol0.000222%
BADD_D00793Equilin sulfate--
BADD_D00802Ertapenem0.000049%
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