Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Diabetic neuropathy
ADR ID BADD_A01253
ADR Hierarchy
05      Endocrine disorders
05.07      Diabetic complications
05.07.04      Diabetic complications neurological
05.07.04.003      Diabetic neuropathy
14      Metabolism and nutrition disorders
14.07      Diabetic complications
14.07.04      Diabetic complications neurological
14.07.04.003      Diabetic neuropathy
17      Nervous system disorders
17.09      Peripheral neuropathies
17.09.04      Chronic polyneuropathies
17.09.04.002      Diabetic neuropathy
Description Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325) [MeSH]
MedDRA Code 10012680
MeSH ID D003929
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Diabetes with neurological manifestations | Diabetic neuropathy | Diabetic peripheral neuropathy | Diabetic polyneuropathy | Polyneuropathy in diabetes | Type I diabetes mellitus with neurological manifestations | Type II diabetes mellitus with neurological manifestations | Diabetic peripheral neuropathic pain | Diabetic Neuropathies | Diabetic Neuropathy | Neuropathies, Diabetic | Neuropathy, Diabetic | Diabetic Autonomic Neuropathy | Autonomic Neuropathies, Diabetic | Autonomic Neuropathy, Diabetic | Diabetic Autonomic Neuropathies | Neuropathies, Diabetic Autonomic | Neuropathy, Diabetic Autonomic | Diabetic Neuralgia | Diabetic Neuralgias | Neuralgias, Diabetic | Diabetic Neuropathy, Painful | Diabetic Neuropathies, Painful | Neuropathies, Painful Diabetic | Neuropathy, Painful Diabetic | Painful Diabetic Neuropathies | Painful Diabetic Neuropathy | Neuralgia, Diabetic | Symmetric Diabetic Proximal Motor Neuropathy | Asymmetric Diabetic Proximal Motor Neuropathy | Diabetic Asymmetric Polyneuropathy | Asymmetric Polyneuropathies, Diabetic | Asymmetric Polyneuropathy, Diabetic | Diabetic Asymmetric Polyneuropathies | Polyneuropathies, Diabetic Asymmetric | Polyneuropathy, Diabetic Asymmetric | Diabetic Mononeuropathy | Diabetic Mononeuropathies | Mononeuropathies, Diabetic | Mononeuropathy, Diabetic | Diabetic Mononeuropathy Simplex | Diabetic Mononeuropathy Simplices | Mononeuropathy Simplex, Diabetic | Mononeuropathy Simplices, Diabetic | Simplex, Diabetic Mononeuropathy | Simplices, Diabetic Mononeuropathy | Diabetic Amyotrophy | Amyotrophies, Diabetic | Amyotrophy, Diabetic | Diabetic Amyotrophies | Diabetic Polyneuropathy | Diabetic Polyneuropathies | Polyneuropathies, Diabetic | Polyneuropathy, Diabetic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000154%
BADD_D00079Alogliptin0.000399%
BADD_D00285Bosentan0.000265%
BADD_D00344Canagliflozin0.000180%
BADD_D00578Dapagliflozin0.000219%
BADD_D00734Duloxetine--
BADD_D00863Extendin-4--
BADD_D00898Finasteride0.000045%
BADD_D00981Gabapentin0.000044%
BADD_D01024Glipizide0.000065%
BADD_D01260Leuprolide acetate0.001434%
BADD_D01322Losartan--
BADD_D01323Losartan potassium--
BADD_D01336Macitentan0.000301%
BADD_D01401Metformin0.000044%
BADD_D01668Pantoprazole0.000036%
BADD_D01834Prednisone--
BADD_D01835Pregabalin0.001281%
BADD_D02026Simvastatin0.000007%
BADD_D02029Sitagliptin0.000133%
BADD_D02058Sorafenib0.000246%
BADD_D02107Tafamidis0.000538%
BADD_D02247Topiramate--
BADD_D02268Treprostinil0.000082%
BADD_D02369Voriconazole0.014521%
BADD_D02434Cinacalcet0.000860%
BADD_D02436Atorvastatin0.000116%
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