Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D000064r,6r-dorzolamide--
BADD_D00019Acebutolol--
BADD_D00020Acebutolol hydrochloride--
BADD_D00036Acitretin--
BADD_D00039Acyclovir0.000071%
BADD_D00046Ado-trastuzumab emtansine--
BADD_D00047Afatinib0.000963%
BADD_D00066Alendronic acid0.000242%
BADD_D00075Alitretinoin--
BADD_D00077Almotriptan--
BADD_D00078Almotriptan malate--
BADD_D00081Alomide--
BADD_D00097Amantadine0.001337%
BADD_D00115Amiodarone0.000404%
BADD_D00121Amlodipine--
BADD_D00132Amphotericin b--
BADD_D00142Anastrozole0.000667%
BADD_D00154Apraclonidine--
BADD_D00156Apremilast--
BADD_D00165Aripiprazole--
BADD_D00168Arsenic--
BADD_D00169Arsenic trioxide--
BADD_D00171Ascorbic acid--
BADD_D00178Atenolol--
BADD_D00182Atorvastatin calcium--
BADD_D00189Atropine--
BADD_D00190Atropine sulfate--
BADD_D00193Axitinib--
BADD_D00203Azithromycin0.000107%
BADD_D00215Bazedoxifene acetate--
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