Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00759Eltrombopag--
BADD_D00763Emedastine--
BADD_D00764Emedastine difumarate--
BADD_D00767Enalapril maleate--
BADD_D00768Enalaprilat--
BADD_D00800Erlotinib0.001175%
BADD_D00801Erlotinib hydrochloride--
BADD_D00809Escitalopram--
BADD_D00821Estradiol0.000209%
BADD_D00837Eszopiclone0.000748%
BADD_D00861Exemestane0.004078%
BADD_D00873Fenofibrate0.000039%
BADD_D00879Fentanyl--
BADD_D00891Fesoterodine0.002679%
BADD_D00892Fesoterodine fumarate--
BADD_D00893Fexofenadine--
BADD_D00898Finasteride0.000917%
BADD_D00912Fluconazole0.000090%
BADD_D00924Fluocinolone acetonide--
BADD_D00932Fluoxetine--
BADD_D00950Fluvoxamine--
BADD_D00951Fluvoxamine maleate--
BADD_D00981Gabapentin--
BADD_D01003Ganciclovir--
BADD_D01004Ganciclovir sodium--
BADD_D01006Gatifloxacin--
BADD_D01008Gefitinib--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01038Goserelin--
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