Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01039Goserelin acetate--
BADD_D01086Hydrocortisone--
BADD_D01096Hydromorphone--
BADD_D01103Hydroxychloroquine0.002789%
BADD_D01114Hyoscyamine--
BADD_D01117Ibandronic acid0.001615%
BADD_D01119Ibrutinib0.001377%
BADD_D01120Ibuprofen--
BADD_D01132Idursulfase--
BADD_D01134Iloperidone--
BADD_D01136Imatinib--
BADD_D01137Imatinib mesylate--
BADD_D01167Interferon alfa-2b--
BADD_D01213Isotretinoin0.058714%
BADD_D01223Ixazomib0.001119%
BADD_D01230Ketoconazole--
BADD_D01231Ketoprofen--
BADD_D01232Ketorolac--
BADD_D01233Ketorolac tromethamine--
BADD_D01234Ketotifen--
BADD_D01236Labetalol--
BADD_D01237Labetalol hydrochloride--
BADD_D01243Lamotrigine--
BADD_D01245Lansoprazole--
BADD_D01250Lasofoxifene--
BADD_D01251Latanoprost0.002195%
BADD_D01253Lenalidomide0.059507%
BADD_D01257Letrozole0.000659%
BADD_D01261Leuprolide monoacetate--
BADD_D01270Levocabastine hydrochloride--
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