Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Duodenal ulcer
ADR ID BADD_A01350
ADR Hierarchy
07      Gastrointestinal disorders
07.04      Gastrointestinal ulceration and perforation
07.04.02      Duodenal ulcers and perforation
07.04.02.002      Duodenal ulcer
Description A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the duodenal wall. [CTCAE] A PEPTIC ULCER located in the DUODENUM. | Acute stress DUODENAL ULCER, usually observed in patients with extensive third-degree burns. [MeSH]
MedDRA Code 10013836
MeSH ID D004381
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute duodenal ulcer | Acute duodenal ulcer without mention of haemorrhage or perforation | Acute duodenal ulcer without mention of hemorrhage or perforation | Acute duodenal ulcer without mention of hemorrhage or perforation, without mention of obstruction | Chronic duodenal ulcer without mention of haemorrhage or perforation | Chronic duodenal ulcer without mention of hemorrhage or perforation | Chronic duodenal ulcer without mention of hemorrhage or perforation, without mention of obstruction | DU | Duodenal ulcer | Duodenal ulcer aggravated | Duodenal ulcer reactivated | Duodenal ulcer, unspec as acute or chronic, w/o hemorrhage or perforation, w/o ment of obstruction | Duodenal ulcer, unspecified as acute or chronic, without mention of haemorrhage or perforation | Duodenal ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation | Reactivated DU | Reactivated duodenal ulcer | Ulcer duodenal | Ulcer duodenal reactivated | Chronic duodenal ulcer without mention of haemorrhage or perforation, without mention of obstruction | Duodenal Ulcer | Duodenal Ulcers | Ulcer, Duodenal | Ulcers, Duodenal | Curling Ulcer | Ulcer, Curling | Curling's Ulcer | Curlings Ulcer
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01120Ibuprofen0.000009%
BADD_D01132Idursulfase--
BADD_D01134Iloperidone--
BADD_D01156Indomethacin--
BADD_D01211Isosorbide mononitrate--
BADD_D01231Ketoprofen0.003361%
BADD_D01232Ketorolac--
BADD_D01233Ketorolac tromethamine--
BADD_D01245Lansoprazole0.000249%
BADD_D01250Lasofoxifene--
BADD_D01252Leflunomide0.000643%
BADD_D01254Lenvatinib0.000392%
BADD_D01261Leuprolide monoacetate--
BADD_D01368Mefenamic acid--
BADD_D01374Meloxicam0.000098%
BADD_D01375Meloxicam sodium--
BADD_D01397Mesalamine--
BADD_D01418Methotrexate--
BADD_D01433Methylprednisolone0.000048%
BADD_D01507Mycophenolate mofetil--
BADD_D01508Mycophenolic acid--
BADD_D01511Nabumetone--
BADD_D01533Naproxen0.000038%
BADD_D01534Naproxen sodium--
BADD_D01567Nilotinib0.000280%
BADD_D01602Olmesartan0.000891%
BADD_D01629Osimertinib0.000246%
BADD_D01635Oxaprozin--
BADD_D01637Oxcarbazepine--
BADD_D01668Pantoprazole0.000025%
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