Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Dyspepsia
ADR ID BADD_A01369
ADR Hierarchy
07      Gastrointestinal disorders
07.01      Gastrointestinal signs and symptoms
07.01.02      Dyspeptic signs and symptoms
07.01.02.001      Dyspepsia
Description A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting. [CTCAE] Impaired digestion, especially after eating. [MeSH]
MedDRA Code 10013946
MeSH ID D004415; D006356
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acid dyspepsia | Acid indigestion | Difficult digestion | Digestion impaired | Distress epigastric | Dyspepsia | Dyspepsia aggravated | Dyspepsia and other specified disorders of function of stomach | Epigastric burning | Epigastric distress | Epigastric food-related pain | Flatulent dyspepsia | Heartburn | Heartburn aggravated | Heartburn-like dyspepsia | Increasing indigestion | Indigestion | Indigestion acid | Indigestion nervous | Pyrosis | Sour stomach | Stomach burning sensation of | Ulcer-like dyspepsia | Waterbrash | Dyspepsia-aggravated | Maldigestion | Functional dyspepsia | Non-ulcer dyspepsia | Chronic heartburn | Gastrooesophageal burning | Gastroesophageal burning | Dyspepsias | Indigestions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01201Isavuconazonium sulfate--
BADD_D01204Isoniazid--
BADD_D01209Isosorbide--
BADD_D01211Isosorbide mononitrate--
BADD_D01216Isradipine--
BADD_D01217Itraconazole--
BADD_D01218Ivabradine0.000575%
BADD_D01223Ixazomib0.001287%
BADD_D01230Ketoconazole--
BADD_D01231Ketoprofen0.006721%
BADD_D01232Ketorolac--
BADD_D01233Ketorolac tromethamine--
BADD_D01236Labetalol--
BADD_D01237Labetalol hydrochloride--
BADD_D01238Lacosamide--
BADD_D01241Lamisil--
BADD_D01242Lamivudine--
BADD_D01243Lamotrigine--
BADD_D01244Lanreotide acetate--
BADD_D01245Lansoprazole0.002456%
BADD_D01246Lanthanum--
BADD_D01247Lanthanum carbonate--
BADD_D01248Lapatinib0.000951%
BADD_D01252Leflunomide--
BADD_D01253Lenalidomide--
BADD_D01254Lenvatinib--
BADD_D01255Lercanidipine--
BADD_D01257Letrozole0.002397%
BADD_D01260Leuprolide acetate--
BADD_D01261Leuprolide monoacetate--
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