Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Dyspepsia
ADR ID BADD_A01369
ADR Hierarchy
07      Gastrointestinal disorders
07.01      Gastrointestinal signs and symptoms
07.01.02      Dyspeptic signs and symptoms
07.01.02.001      Dyspepsia
Description A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting. [CTCAE] Impaired digestion, especially after eating. [MeSH]
MedDRA Code 10013946
MeSH ID D004415; D006356
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acid dyspepsia | Acid indigestion | Difficult digestion | Digestion impaired | Distress epigastric | Dyspepsia | Dyspepsia aggravated | Dyspepsia and other specified disorders of function of stomach | Epigastric burning | Epigastric distress | Epigastric food-related pain | Flatulent dyspepsia | Heartburn | Heartburn aggravated | Heartburn-like dyspepsia | Increasing indigestion | Indigestion | Indigestion acid | Indigestion nervous | Pyrosis | Sour stomach | Stomach burning sensation of | Ulcer-like dyspepsia | Waterbrash | Dyspepsia-aggravated | Maldigestion | Functional dyspepsia | Non-ulcer dyspepsia | Chronic heartburn | Gastrooesophageal burning | Gastroesophageal burning | Dyspepsias | Indigestions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01322Losartan0.000098%
BADD_D01323Losartan potassium--
BADD_D01325Lovastatin--
BADD_D01328Lubiprostone--
BADD_D01330Lurasidone--
BADD_D01331Lurasidone hydrochloride--
BADD_D01335Lyxumia--
BADD_D01336Macitentan0.006968%
BADD_D01350Maprotiline--
BADD_D01351Maprotiline hydrochloride--
BADD_D01354Mebeverine--
BADD_D01363Meclofenamate sodium--
BADD_D01365Medroxyprogesterone--
BADD_D01366Medroxyprogesterone acetate--
BADD_D01368Mefenamic acid--
BADD_D01369Mefloquine--
BADD_D01370Mefloquine hydrochloride--
BADD_D01371Megestrol--
BADD_D01372Megestrol acetate--
BADD_D01373Melatonin--
BADD_D01374Meloxicam0.000051%
BADD_D01375Meloxicam sodium--
BADD_D01376Melphalan0.000336%
BADD_D01378Memantine--
BADD_D01381Mepact--
BADD_D01391Mercaptoethanesulfonic acid--
BADD_D01392Mercaptopurine--
BADD_D01393Meropenem--
BADD_D01394Merrem i.v.--
BADD_D01397Mesalamine0.001610%
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