Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Dysphagia
ADR ID BADD_A01371
ADR Hierarchy
07      Gastrointestinal disorders
07.01      Gastrointestinal signs and symptoms
07.01.06      Gastrointestinal signs and symptoms NEC
07.01.06.003      Dysphagia
Description A disorder characterized by difficulty in swallowing. [CTCAE] Difficulty in SWALLOWING which may result from neuromuscular disorder or mechanical obstruction. Dysphagia is classified into two distinct types: oropharyngeal dysphagia due to malfunction of the PHARYNX and UPPER ESOPHAGEAL SPHINCTER; and esophageal dysphagia due to malfunction of the ESOPHAGUS. [MeSH]
MedDRA Code 10013950
MeSH ID D003680
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Deglutition disorder | Disorder deglutition | Dysphagia | Swallowing difficult | Swallowing disorder | Swallowing impaired | Swallowing spasm | Dysphagia aggravated | Aphagia | Oropharyngeal dysphagia | Esophageal dysphagia | Oesophageal dysphagia | Unable to swallow | Pharyngoesophageal dysphagia | Pharyngo-oesophageal dysphagia | Deglutition Disorders | Deglutition Disorder | Disorders, Deglutition | Swallowing Disorders | Swallowing Disorder | Oropharyngeal Dysphagia | Dysphagia, Oropharyngeal | Esophageal Dysphagia | Dysphagia, Esophageal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02445Solifenacin0.002691%
BADD_D02451Pimavanserin0.016424%
BADD_D02453Midostaurin0.004085%
BADD_D02457Dexmethylphenidate0.002608%
BADD_D02464Fingolimod0.020712%
BADD_D02467Naloxegol0.001712%
BADD_D02469Edoxaban0.000222%
BADD_D02470Nintedanib0.002530%
BADD_D02472Sonidegib0.000246%
BADD_D02473Sodium chloride--
BADD_D02480Alectinib0.003492%
BADD_D02482Acalabrutinib0.001399%
BADD_D02483Ribociclib0.005753%
BADD_D02484Istradefylline0.002972%
BADD_D02485Talazoparib0.000437%
BADD_D02489Neratinib0.000548%
BADD_D02490Apalutamide0.006206%
BADD_D02491Valbenazine0.024495%
BADD_D02492Deflazacort0.000641%
BADD_D02498Abemaciclib0.002071%
BADD_D02500Alpelisib0.004220%
BADD_D02502Letermovir0.002343%
BADD_D02504Lorlatinib0.001589%
BADD_D02505Gilteritinib0.000907%
BADD_D02507Deutetrabenazine0.009583%
BADD_D02508Edaravone0.002100%
BADD_D02509Brigatinib0.001075%
BADD_D02510Rucaparib0.002821%
BADD_D02515Pexidartinib0.000381%
BADD_D02524Ivosidenib0.001254%
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