Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Encephalopathy
ADR ID BADD_A01462
ADR Hierarchy
17      Nervous system disorders
17.13      Encephalopathies
17.13.02      Encephalopathies NEC
17.13.02.001      Encephalopathy
Description A disorder characterized by a pathologic process involving the brain. [CTCAE] Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. [MeSH]
MedDRA Code 10014625
MeSH ID D001927
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Encephalopathy | Encephalopathy acute | Encephalopathy chronic | Encephalopathy NOS | Encephalopathy, unspecified | Influenza encephalopathy | Static encephalopathy | Mixed-type encephalopathy | Brain Diseases | Brain Disease | Brain Disorders | Brain Disorder | Intracranial CNS Disorders | Central Nervous System Intracranial Disorders | CNS Disorders, Intracranial | CNS Disorder, Intracranial | Intracranial CNS Disorder | Encephalon Diseases | Encephalon Disease | Intracranial Central Nervous System Disorders | Central Nervous System Disorders, Intracranial | Encephalopathies
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01898Rabeprazole0.000391%
BADD_D01922Regorafenib0.000951%
BADD_D01933Ribavirin0.114719%
BADD_D01938Rifaximin0.000965%
BADD_D01951Risperidone0.001818%
BADD_D01970Rosiglitazone maleate--
BADD_D02002Selegiline--
BADD_D02015Sevoflurane0.000268%
BADD_D02033Sodium aurothiomalate--
BADD_D02034Sodium bicarbonate0.002349%
BADD_D02053Sofosbuvir0.002964%
BADD_D02058Sorafenib0.001813%
BADD_D02066Spironolactone0.000128%
BADD_D02069Stiripentol0.000125%
BADD_D02093Sulfasalazine0.000606%
BADD_D02105Tacrolimus0.007426%
BADD_D02106Tadalafil0.000683%
BADD_D02147Telmisartan0.000260%
BADD_D02154Tenofovir0.005816%
BADD_D02203Thiotepa--
BADD_D02210Tiagabine--
BADD_D02211Tiagabine hydrochloride--
BADD_D02241Tolcapone--
BADD_D02246Tolvaptan0.000145%
BADD_D02247Topiramate0.000362%
BADD_D02253Trabectedin0.000112%
BADD_D02254Tramadol0.000036%
BADD_D02261Tranexamic acid0.009352%
BADD_D02270Tretinoin--
BADD_D02307Trovafloxacin--
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ADReCS-Target
ADR Term Drug Name Target