Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00760Eltrombopag olamine--
BADD_D00761Eluxadoline--
BADD_D00762Elvitegravir--
BADD_D00766Emtricitabine--
BADD_D00767Enalapril maleate--
BADD_D00768Enalaprilat--
BADD_D00771Enfuvirtide--
BADD_D00773Entacapone--
BADD_D00774Entecavir--
BADD_D00775Enzalutamide0.301177%
BADD_D00776Eovist--
BADD_D00779Epi-kal2--
BADD_D00784Epirubicin--
BADD_D00785Epirubicin hydrochloride--
BADD_D00786Eplerenone--
BADD_D00788Epoprostenol0.004458%
BADD_D00789Epoprostenol sodium--
BADD_D00790Eprosartan--
BADD_D00791Eprosartan mesylate--
BADD_D00793Equilin sulfate--
BADD_D00794Ergocalciferol0.012515%
BADD_D00798Eribulin--
BADD_D00799Eribulin mesylate--
BADD_D00800Erlotinib--
BADD_D00801Erlotinib hydrochloride--
BADD_D00802Ertapenem--
BADD_D00803Ertapenem sodium--
BADD_D00809Escitalopram--
BADD_D00810Escitalopram oxalate--
BADD_D00811Eslicarbazepine--
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ADReCS-Target
ADR Term Drug Name Target