Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00071Alglucosidase alfa--
BADD_D00073Aliskiren0.001828%
BADD_D00074Aliskiren hemifumarate--
BADD_D00075Alitretinoin--
BADD_D00077Almotriptan--
BADD_D00078Almotriptan malate--
BADD_D00081Alomide--
BADD_D00082Alosetron--
BADD_D00085Alprazolam--
BADD_D00088Altretamine--
BADD_D00097Amantadine--
BADD_D00098Amantadine hydrochloride--
BADD_D00100Ambrisentan0.075863%
BADD_D00103Amikacin0.003842%
BADD_D00105Amiloride hydrochloride--
BADD_D00115Amiodarone0.016659%
BADD_D00116Amiodarone hydrochloride--
BADD_D00117Amisulpride--
BADD_D00118Amitriptyline--
BADD_D00119Amitriptyline hydrochloride--
BADD_D00121Amlodipine--
BADD_D00122Amlodipine besylate--
BADD_D00128Amoxapine--
BADD_D00129Amoxicillin--
BADD_D00130Amphetamine--
BADD_D00136Amprenavir--
BADD_D00137Amsacrine--
BADD_D00139Anagrelide--
BADD_D00140Anagrelide hydrochloride--
BADD_D00142Anastrozole--
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ADReCS-Target
ADR Term Drug Name Target