Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00346Candesartan--
BADD_D00347Candesartan cilexetil--
BADD_D00349Capecitabine0.039097%
BADD_D00354Captopril--
BADD_D00356Carbamazepine--
BADD_D00359Carbidopa--
BADD_D00361Carbinoxamine--
BADD_D00362Carbinoxamine maleate--
BADD_D00363Carbonic acid--
BADD_D00364Carboplatin--
BADD_D00367Carfilzomib0.038190%
BADD_D00369Cariprazine--
BADD_D00374Carvedilol--
BADD_D00375Carvedilol phosphate--
BADD_D00376Caspofungin--
BADD_D00377Caspofungin acetate--
BADD_D00382Cefazolin--
BADD_D00395Cefpodoxime--
BADD_D00401Ceftibuten dihydrate--
BADD_D00404Ceftobiprole--
BADD_D00410Celecoxib--
BADD_D00411Celiprolol--
BADD_D00412Cephalexin--
BADD_D00414Ceritinib0.003156%
BADD_D00415Cerivastatin--
BADD_D00416Certolizumab pegol--
BADD_D00417Cetirizine--
BADD_D00418Cetirizine hydrochloride--
BADD_D00422Cetuximab--
BADD_D00424Cevimeline--
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ADReCS-Target
ADR Term Drug Name Target