Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Fracture
ADR ID BADD_A01693
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.04      Bone and joint injuries
12.04.02      Fractures and dislocations NEC
12.04.02.001      Fracture
15      Musculoskeletal and connective tissue disorders
15.08      Fractures
15.08.02      Fractures NEC
15.08.02.001      Fracture
Description A finding of traumatic injury to the bone in which the continuity of the bone is broken. [CTCAE] Fractures in which the break in bone is not accompanied by an external wound. [MeSH]
MedDRA Code 10017076
MeSH ID D005596
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Bone fracture (not spontaneous) | Fracture | Fracture bone | Fracture NOS | Fracture of bones of trunk, closed | Fracture of unspecified bone, closed | Fracture of unspecified bones | Ill-defined fractures of bones of trunk | Late effect of fracture of multiple and unspecified bones | Bone splinter | Closed fracture | Occult fracture | Diaphyseal fracture | Subchondral fracture | Fractures, Closed | Closed Fracture | Closed Fractures | Fracture, Closed | Fractures, Occult | Fracture, Occult | Occult Fracture | Occult Fractures
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01261Leuprolide monoacetate--
BADD_D01378Memantine--
BADD_D01379Memantine hydrochloride--
BADD_D01405Methadone--
BADD_D01418Methotrexate--
BADD_D01433Methylprednisolone--
BADD_D01459Midazolam--
BADD_D01558Nexium--
BADD_D01595Octreotide acetate--
BADD_D01610Omalizumab--
BADD_D01614Omeprazole--
BADD_D01615Omeprazole magnesium--
BADD_D01624Orlistat--
BADD_D01637Oxcarbazepine--
BADD_D01668Pantoprazole--
BADD_D01669Pantoprazole sodium--
BADD_D01679Paroxetine--
BADD_D01765Phenytoin--
BADD_D01766Phenytoin sodium--
BADD_D01777Pioglitazone--
BADD_D01778Pioglitazone hydrochloride--
BADD_D01834Prednisone--
BADD_D01898Rabeprazole--
BADD_D01899Rabeprazole sodium--
BADD_D01937Rifapentine--
BADD_D01950Risedronic acid--
BADD_D01956Rivastigmine tartrate--
BADD_D01970Rosiglitazone maleate--
BADD_D01992Saxagliptin--
BADD_D02011Sertraline hydrochloride--
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